Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update

Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update

Fever and neutropenia (FN) is one of the most common complications of cancer treatments. The management of pediatric FN continues to be heterogeneous across and within centers1-4; this heterogeneity can be reduced through implementation of clinical practice guidelines (CPGs). CPGs are important to direct clinical care that is evidence-based, and CPG-consistent care can improve outcomes in FN.5 Our original CPG on the management of FN in pediatric cancer and hematopoietic cell transplant (HCT) recipients was published in 20126 and updated in 2017.7 The objective was to update this CPG for the empiric management of FN in pediatric patients with cancer and HCT recipients.