Pharmacokinetic evaluation of twice-a-week micafungin for prophylaxis of invasive fungal disease in children with acute lymphoblastic leukaemia: a prospective observational cohort study

Pharmacokinetic evaluation of twice-a-week micafungin for prophylaxis of invasive fungal disease in children with acute lymphoblastic leukaemia: a prospective observational cohort study Objectives: To determine the pharmacokinetics of twice-a-week micafungin...

Optimal Management of Complicated Infections in the Pediatric Patient: The Role and Utility of Ceftazidime/Avibactam

Optimal Management of Complicated Infections in the Pediatric Patient: The Role and Utility of Ceftazidime/Avibactam Abstract: Antimicrobial resistance poses a substantial threat to global public health. The pursuit of new antibiotics has decreased and very few...

Challenges in the Treatment of Invasive Aspergillosis in Immunocompromised Children

Challenges in the Treatment of Invasive Aspergillosis in Immunocompromised Children ABSTRACT Invasive aspergillosis (IA) is associated with significant morbidity and mortality. Voriconazole remains the drug of choice for the treatment of IA in children; however, the...

Escherichia Coli Meningitis Features in 325 Children From 2001 to 2013 in France

Escherichia Coli Meningitis Features in 325 Children From 2001 to 2013 in France Background. We aimed to describe features of Escherichia coli meningitis in a large population of children and the molecular characteristics of the involved strains to determine factors...

CMV in pediatric patients

CMV in pediatric patients Purpose of review The purpose of this study is to explore the latest developments in the risk factors, prevention and treatment of cytomegalovirus (CMV) infection in immunocompromised children, including those with congenital immunodeficiency...

The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation

 The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common complications affecting solid organ transplant recipients,...

Pneumocystis jiroveci in Solid Organ Transplantation

Pneumocystis jiroveci in Solid Organ Transplantation Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice Provided by : Dr Rana Maghrabi Read...

Tissue Penetration of Antifungal Agents

Tissue Penetration of Antifungal Agents Timothy Felton Peter. Troke, William . Hope The University of Manchester, Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom; Antimicrobial Pharmacodynamics...

International Journal of Pediatrics and Adolescent Medicine

International Journal of Pediatrics and Adolescent Medicine Management of community-acquired pneumonia in infants and children: The World Health Organization (WHO) has reported that pneumonia continues to be a significant cause of mortality in the pediatric age group...

INFECTIONS IN TRANSPLANT PT

Prevention and Treatment of Infectious Complications After Solid Organ Transplantation in Children Organ transplantation is the most practical means of rehabilitating patients with a variety of forms of end organ dysfunction. This procedure is arguably the outstanding...